(This article has been Updated and Edited to make it a better article. Ed.)
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A cool discovery for all you sleepy heads out there: Orexin A
A nasal spray containing a naturally occurring brain hormone called orexin A reversed the effects of sleep deprivation in monkeys, allowing them to perform like well-rested monkeys on cognitive tests. The discovery’s first application will probably be in treatment of the severe sleep disorder narcolepsy.
The treatment is “a totally new route for increasing arousal, and the new study shows it to be relatively benign,” said Jerome Siegel, a professor of psychiatry at UCLA and a co-author of the paper. “It reduces sleepiness without causing edginess.”
I find a spray that will allow me to perform like a well-rested monkey to be very appealing. So I wonder where someone might find some orexin A because if someone wants to try orexin A, too bad.
Sleep advocates probably won’t have to worry about orexin A reaching drugstore shelves for many years. Any commercial treatment using the substance would need approval from the Food and Drug Administration, which can take more than a decade.
Personally, I am a sleep advocate. After hours of hard work tiring the mind and body almost nothing in the world feels better than to sink into a comfortable bed to sleep. But that is not how I’ve been operating for the past many months. Of late, I go to bed on a schedule that gives me enough sleep to get up at 5:30 AM, plod through a fairly tightly scheduled day and then back to bed at the scheduled hour. Repeat five times. For whatever reason I am tired all the time and in that tiny little bit of time I have to myself before bedtime I don’t feel like doing anything.
I think my preferred survival pattern is to work till I fall then get up and work till I fall and repeat until I have enough money to go somewhere and play till I fall, get up and play till I fall, until I have to go back to work. Repeat.
Either way, when I am not sleeping I need to be wide-awake and energized. Know what I mean? I remember back when I was just a young ‘un Doctors would give amphetamines to Gramma, who was a temperate woman by any other measure. She called the prescribed pills her go-fast pills. We were just kids and thought that was some funny stuff… until we were a little bit older. Gramma was a housekeeper second to none in those years, let me tell you.
Anyone remember in the seventies those little chocolate candies that were sold as diet aids? I disremember if it was my grandmother or mother who took those, but I believe the diet aide’s unfortunate name was actually Aids and they came packaged in a deep red velvet colored box fashioned like a regular Russel Stover’s box. Brilliant marketing , no? Except for the unfortunate name. I don’t know if there was any good drugs in those little candies or if they were just laced with caffeine but we would sneak them just because they were chocolate/caramel-like. We’d sneak em from the top of the closet, up there next to the mountains of redeemable grocery store stamps, wigs, and rifle ammo.
Anyway, the point being, my grandma lived to be eighty-six years old. Until the last year of her life she gallivanted around the country like a Grand Duchess. The way I feel right now I don’t know if I want to make it to sixty. It is time to get rid of the war on drugs. It is time to get rid of strict government control of every single substance that may be taken into the body. I say break out the orexin A. Break out the Modafinil. Break out the amphetamines. Break out the miracle creams that propel people to athletic super stardom. End the criminalization of vast portions of our society so that these beneficial drugs can be administered and monitored by qualified physicians for which we already pay an arm and a leg.
I’d rather be healthy and active till I’m sixty-five than live to be 80 in this old crumpled down body. I’m sure my outlook would be different if I were already 60 but ideally I would like to live a healthy and active 80 years, maybe more as long as I don’t have to see my legacy perish. I can live with a little edginess.
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